Gut Microbiome of an 11th Century A.D. Pre-Columbian Andean Mummy
Identifieur interne : 000149 ( Main/Exploration ); précédent : 000148; suivant : 000150Gut Microbiome of an 11th Century A.D. Pre-Columbian Andean Mummy
Auteurs : Tasha M. Santiago-Rodriguez [États-Unis] ; Gino Fornaciari [Italie] ; Stefania Luciani [Italie] ; Scot E. Dowd [États-Unis] ; Gary A. Toranzos ; Isolina Marota [Italie] ; Raul J. Cano [États-Unis]Source :
- PLoS ONE [ 1932-6203 ] ; 2015.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : RNA, Bacterial, RNA, Ribosomal, 16S.
- genetics : Clostridium, Drug Resistance, Bacterial.
- microbiology : Mummies.
- Gastrointestinal Microbiome, Humans.
Abstract
The process of natural mummification is a rare and unique process from which little is known about the resulting microbial community structure. In the present study, we characterized the microbiome of paleofeces, and ascending, transverse and descending colon of an 11th century A.D. pre-Columbian Andean mummy by 16S rRNA gene high-throughput sequencing and metagenomics. Firmicutes were the most abundant bacterial group, with
Url:
DOI: 10.1371/journal.pone.0138135
PubMed: 26422376
PubMed Central: 4589460
Affiliations:
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Dowd</name><affiliation wicri:level="2"><nlm:aff id="aff005"><addr-line>Molecular Research LP (MR DNA), Shallowater, Texas, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Molecular Research LP (MR DNA), Shallowater, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Toranzos, Gary A" sort="Toranzos, Gary A" uniqKey="Toranzos G" first="Gary A." last="Toranzos">Gary A. Toranzos</name><affiliation><nlm:aff id="aff006"><addr-line>Department of Biology, University of Puerto Rico, San Juan, PR</addr-line></nlm:aff><wicri:noCountry code="subfield">PR</wicri:noCountry></affiliation></author><author><name sortKey="Marota, Isolina" sort="Marota, Isolina" uniqKey="Marota I" first="Isolina" last="Marota">Isolina Marota</name><affiliation wicri:level="1"><nlm:aff id="aff004"><addr-line>Laboratory of Molecular Archaeo-Anthropology/ancient DNA, School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy</addr-line></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Molecular Archaeo-Anthropology/ancient DNA, School of Biosciences and Veterinary Medicine, University of Camerino, Camerino</wicri:regionArea><wicri:noRegion>Camerino</wicri:noRegion></affiliation></author><author><name sortKey="Cano, Raul J" sort="Cano, Raul J" uniqKey="Cano R" first="Raul J." last="Cano">Raul J. Cano</name><affiliation wicri:level="2"><nlm:aff id="aff007"><addr-line>Center for Applications in Biotechnology, California Polytechnic State University, San Luis Obispo, CA, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Applications in Biotechnology, California Polytechnic State University, San Luis Obispo, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author></analytic><series><title level="j">PLoS ONE</title><idno type="eISSN">1932-6203</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Clostridium (genetics)</term><term>Drug Resistance, Bacterial (genetics)</term><term>Gastrointestinal Microbiome</term><term>Humans</term><term>Mummies (microbiology)</term><term>RNA, Bacterial (genetics)</term><term>RNA, Ribosomal, 16S (genetics)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>RNA, Bacterial</term><term>RNA, Ribosomal, 16S</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Clostridium</term><term>Drug Resistance, Bacterial</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Mummies</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Gastrointestinal Microbiome</term><term>Humans</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The process of natural mummification is a rare and unique process from which little is known about the resulting microbial community structure. In the present study, we characterized the microbiome of paleofeces, and ascending, transverse and descending colon of an 11<sup>th</sup> century A.D. pre-Columbian Andean mummy by 16S rRNA gene high-throughput sequencing and metagenomics. Firmicutes were the most abundant bacterial group, with <italic>Clostridium</italic> spp. comprising up to 96.2% of the mummified gut, while <italic>Turicibacter</italic> spp. represented 89.2% of the bacteria identified in the paleofeces. Microbiome profile of the paleofeces was unique when compared to previously characterized coprolites that did not undergo natural mummification. We identified DNA sequences homologous to <italic>Clostridium botulinum</italic>, <italic>Trypanosoma cruzi</italic> and human papillomaviruses (HPVs). Unexpectedly, putative antibiotic-resistance genes including beta-lactamases, penicillin-binding proteins, resistance to fosfomycin, chloramphenicol, aminoglycosides, macrolides, sulfa, quinolones, tetracycline and vancomycin, and multi-drug transporters, were also identified. The presence of putative antibiotic-resistance genes suggests that resistance may not necessarily be associated with a selective pressure of antibiotics or contact with European cultures. Identification of pathogens and antibiotic-resistance genes in ancient human specimens will aid in the understanding of the evolution of pathogens as a way to treat and prevent diseases caused by bacteria, microbial eukaryotes and viruses.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Turnbaugh, Pj" uniqKey="Turnbaugh P">PJ Turnbaugh</name></author><author><name sortKey="Hamady, M" uniqKey="Hamady M">M Hamady</name></author><author><name sortKey="Yatsunenko, T" uniqKey="Yatsunenko T">T Yatsunenko</name></author><author><name sortKey="Cantarel, Bl" uniqKey="Cantarel B">BL Cantarel</name></author><author><name sortKey="Duncan, A" uniqKey="Duncan A">A Duncan</name></author><author><name sortKey="Ley, Re" uniqKey="Ley R">RE Ley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Michail, S" uniqKey="Michail S">S Michail</name></author><author><name sortKey="Durbin, M" uniqKey="Durbin M">M Durbin</name></author><author><name sortKey="Turner, D" uniqKey="Turner D">D Turner</name></author><author><name sortKey="Griffiths, Am" uniqKey="Griffiths A">AM Griffiths</name></author><author><name sortKey="Mack, Dr" uniqKey="Mack D">DR Mack</name></author><author><name sortKey="Hyams, J" uniqKey="Hyams J">J Hyams</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mulle, Jg" uniqKey="Mulle J">JG Mulle</name></author><author><name sortKey="Sharp, Wg" uniqKey="Sharp W">WG Sharp</name></author><author><name sortKey="Cubells, Jf" uniqKey="Cubells J">JF Cubells</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Markle, Jg" uniqKey="Markle J">JG Markle</name></author><author><name sortKey="Frank, Dn" uniqKey="Frank D">DN Frank</name></author><author><name sortKey="Mortin Toth, S" uniqKey="Mortin Toth S">S Mortin-Toth</name></author><author><name sortKey="Robertson, Ce" uniqKey="Robertson C">CE Robertson</name></author><author><name sortKey="Feazel, Lm" uniqKey="Feazel L">LM Feazel</name></author><author><name sortKey="Rolle Kampczyk, U" uniqKey="Rolle Kampczyk U">U Rolle-Kampczyk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ahn, J" uniqKey="Ahn J">J Ahn</name></author><author><name sortKey="Sinha, R" uniqKey="Sinha R">R Sinha</name></author><author><name sortKey="Pei, Z" uniqKey="Pei Z">Z Pei</name></author><author><name sortKey="Dominianni, C" uniqKey="Dominianni C">C Dominianni</name></author><author><name sortKey="Wu, J" uniqKey="Wu J">J Wu</name></author><author><name sortKey="Shi, J" uniqKey="Shi J">J Shi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Larsen, N" uniqKey="Larsen N">N Larsen</name></author><author><name sortKey="Vogensen, Fk" uniqKey="Vogensen F">FK Vogensen</name></author><author><name sortKey="Van Den Berg, Fw" uniqKey="Van Den Berg F">FW van den Berg</name></author><author><name sortKey="Nielsen, Ds" uniqKey="Nielsen D">DS Nielsen</name></author><author><name sortKey="Andreasen, As" uniqKey="Andreasen A">AS Andreasen</name></author><author><name sortKey="Pedersen, Bk" uniqKey="Pedersen B">BK Pedersen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Greenblum, S" uniqKey="Greenblum S">S Greenblum</name></author><author><name sortKey="Turnbaugh, Pj" uniqKey="Turnbaugh P">PJ Turnbaugh</name></author><author><name sortKey="Borenstein, E" uniqKey="Borenstein E">E Borenstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cano, Rj" uniqKey="Cano R">RJ Cano</name></author><author><name sortKey="Rivera Perez, J" uniqKey="Rivera Perez J">J Rivera-Perez</name></author><author><name sortKey="Toranzos, Ga" uniqKey="Toranzos G">GA Toranzos</name></author><author><name sortKey="Santiago Rodriguez, Tm" uniqKey="Santiago Rodriguez T">TM 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sortKey="Weyrich, Ls" uniqKey="Weyrich L">LS Weyrich</name></author><author><name sortKey="Kaidonis, J" uniqKey="Kaidonis J">J Kaidonis</name></author><author><name sortKey="Walker, Aw" uniqKey="Walker A">AW Walker</name></author><author><name sortKey="Haak, W" uniqKey="Haak W">W Haak</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Warinner, C" uniqKey="Warinner C">C Warinner</name></author><author><name sortKey="Rodrigues, Jf" uniqKey="Rodrigues J">JF Rodrigues</name></author><author><name sortKey="Vyas, R" uniqKey="Vyas R">R Vyas</name></author><author><name sortKey="Trachsel, C" uniqKey="Trachsel C">C Trachsel</name></author><author><name sortKey="Shved, N" uniqKey="Shved N">N Shved</name></author><author><name sortKey="Grossmann, J" uniqKey="Grossmann J">J Grossmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="D Osta, Vm" uniqKey="D Osta V">VM D’Costa</name></author><author><name sortKey="King, Ce" uniqKey="King C">CE King</name></author><author><name sortKey="Kalan, L" uniqKey="Kalan L">L Kalan</name></author><author><name sortKey="Morar, M" uniqKey="Morar M">M Morar</name></author><author><name sortKey="Sung, Ww" uniqKey="Sung W">WW Sung</name></author><author><name sortKey="Schwarz, C" uniqKey="Schwarz C">C Schwarz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Santiago Rodriguez, Tm" uniqKey="Santiago Rodriguez T">TM Santiago-Rodriguez</name></author><author><name sortKey="Narganes Storde, Ym" uniqKey="Narganes Storde Y">YM Narganes-Storde</name></author><author><name sortKey="Chanlatte, L" uniqKey="Chanlatte L">L Chanlatte</name></author><author><name sortKey="Crespo Torres, E" uniqKey="Crespo Torres E">E Crespo-Torres</name></author><author><name sortKey="Toranzos, Ga" uniqKey="Toranzos G">GA Toranzos</name></author><author><name sortKey="Jimenez Flores, R" uniqKey="Jimenez Flores R">R Jimenez-Flores</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Santiago Rodriguez, Tm" uniqKey="Santiago Rodriguez T">TM Santiago-Rodriguez</name></author><author><name sortKey="Patricio, Ar" uniqKey="Patricio A">AR Patricio</name></author><author><name sortKey="Rivera, Ji" uniqKey="Rivera J">JI Rivera</name></author><author><name sortKey="Coradin, M" uniqKey="Coradin M">M Coradin</name></author><author><name sortKey="Gonzalez, A" uniqKey="Gonzalez A">A Gonzalez</name></author><author><name sortKey="Tirado, G" uniqKey="Tirado G">G Tirado</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Greenblatt, Cl" uniqKey="Greenblatt C">CL Greenblatt</name></author><author><name sortKey="Davis, A" uniqKey="Davis A">A Davis</name></author><author><name sortKey="Clement, Bg" uniqKey="Clement B">BG Clement</name></author><author><name sortKey="Kitts, Cl" uniqKey="Kitts C">CL Kitts</name></author><author><name sortKey="Cox, T" uniqKey="Cox T">T Cox</name></author><author><name sortKey="Cano, Rj" uniqKey="Cano R">RJ Cano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lambert, Lh" uniqKey="Lambert L">LH Lambert</name></author><author><name sortKey="Cox, T" uniqKey="Cox T">T Cox</name></author><author><name sortKey="Mitchell, K" uniqKey="Mitchell K">K Mitchell</name></author><author><name sortKey="Rossello Mora, Ra" uniqKey="Rossello Mora R">RA Rossello-Mora</name></author><author><name sortKey="Del Cueto, C" uniqKey="Del Cueto C">C Del Cueto</name></author><author><name sortKey="Dodge, De" uniqKey="Dodge D">DE Dodge</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ubaldi, M" uniqKey="Ubaldi M">M Ubaldi</name></author><author><name sortKey="Luciani, S" uniqKey="Luciani S">S Luciani</name></author><author><name sortKey="Marota, I" uniqKey="Marota I">I Marota</name></author><author><name sortKey="Fornaciari, G" uniqKey="Fornaciari G">G Fornaciari</name></author><author><name sortKey="Cano, Rj" uniqKey="Cano R">RJ Cano</name></author><author><name sortKey="Rollo, F" uniqKey="Rollo F">F Rollo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cano, Rj" uniqKey="Cano R">RJ Cano</name></author><author><name sortKey="Tiefenbrunner, F" uniqKey="Tiefenbrunner F">F Tiefenbrunner</name></author><author><name sortKey="Ubaldi, M" uniqKey="Ubaldi M">M Ubaldi</name></author><author><name sortKey="Del Cueto, C" uniqKey="Del Cueto C">C Del Cueto</name></author><author><name sortKey="Luciani, S" uniqKey="Luciani S">S Luciani</name></author><author><name sortKey="Cox, T" uniqKey="Cox T">T Cox</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Janaway, Rc" uniqKey="Janaway R">RC Janaway</name></author><author><name sortKey="Wilson, As" uniqKey="Wilson A">AS Wilson</name></author><author><name sortKey="Diaz, Gc" uniqKey="Diaz G">GC Díaz</name></author><author><name sortKey="Guillen, S" uniqKey="Guillen S">S Guillen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Luciani, S" uniqKey="Luciani S">S Luciani</name></author><author><name sortKey="Fornaciari, G" uniqKey="Fornaciari G">G Fornaciari</name></author><author><name sortKey="Rickards, O" uniqKey="Rickards O">O Rickards</name></author><author><name sortKey="Labarga, Cm" uniqKey="Labarga C">CM Labarga</name></author><author><name sortKey="Rollo, F" uniqKey="Rollo F">F Rollo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rollo, F" uniqKey="Rollo F">F Rollo</name></author><author><name sortKey="Luciani, S" uniqKey="Luciani S">S Luciani</name></author><author><name sortKey="Canapa, A" uniqKey="Canapa A">A Canapa</name></author><author><name sortKey="Marota, I" uniqKey="Marota I">I Marota</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fornaciari, G" uniqKey="Fornaciari G">G Fornaciari</name></author><author><name sortKey="Castagna, M" uniqKey="Castagna M">M Castagna</name></author><author><name sortKey="Viacava, P" uniqKey="Viacava P">P Viacava</name></author><author><name sortKey="Tognetti, A" uniqKey="Tognetti A">A Tognetti</name></author><author><name sortKey="Bevilacqua, G" uniqKey="Bevilacqua G">G Bevilacqua</name></author><author><name sortKey="Segura, E" uniqKey="Segura E">E Segura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fornaciari, G" uniqKey="Fornaciari G">G Fornaciari</name></author><author><name sortKey="Castagna, M" uniqKey="Castagna M">M Castagna</name></author><author><name sortKey="Viacava, P" uniqKey="Viacava P">P Viacava</name></author><author><name sortKey="Tognetti, A" uniqKey="Tognetti A">A Tognetti</name></author><author><name sortKey="Esteva, M" uniqKey="Esteva M">M Esteva</name></author><author><name sortKey="Segura, El" uniqKey="Segura E">EL Segura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rassi, A" uniqKey="Rassi A">A Rassi</name></author><author><name sortKey="Marin Neto, Ja" uniqKey="Marin Neto J">JA Marin-Neto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wilson, Mr" uniqKey="Wilson M">MR Wilson</name></author><author><name sortKey="Naccache, Sn" uniqKey="Naccache S">SN Naccache</name></author><author><name sortKey="Samayoa, E" uniqKey="Samayoa E">E Samayoa</name></author><author><name sortKey="Biagtan, M" uniqKey="Biagtan M">M Biagtan</name></author><author><name sortKey="Bashir, H" uniqKey="Bashir H">H Bashir</name></author><author><name sortKey="Yu, G" uniqKey="Yu G">G Yu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dunne, Wm" uniqKey="Dunne W">WM Dunne</name></author><author><name sortKey="Westblade, Lf" uniqKey="Westblade L">LF Westblade</name></author><author><name sortKey="Ford, B" uniqKey="Ford B">B Ford</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fornaciari, G" uniqKey="Fornaciari G">G Fornaciari</name></author><author><name sortKey="Castagna, M" uniqKey="Castagna M">M Castagna</name></author><author><name sortKey="Viacava, P" uniqKey="Viacava P">P Viacava</name></author><author><name sortKey="Tognetti, A" uniqKey="Tognetti A">A Tognetti</name></author><author><name sortKey="Bevilacqua, G" uniqKey="Bevilacqua G">G Bevilacqua</name></author><author><name sortKey="Segura, El" uniqKey="Segura E">EL Segura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Caporaso, Jg" uniqKey="Caporaso J">JG Caporaso</name></author><author><name sortKey="Kuczynski, J" uniqKey="Kuczynski J">J Kuczynski</name></author><author><name sortKey="Stombaugh, J" uniqKey="Stombaugh J">J Stombaugh</name></author><author><name sortKey="Bittinger, K" uniqKey="Bittinger K">K Bittinger</name></author><author><name sortKey="Bushman, Fd" uniqKey="Bushman F">FD Bushman</name></author><author><name sortKey="Costello, Ek" uniqKey="Costello E">EK Costello</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Knights, D" uniqKey="Knights D">D Knights</name></author><author><name sortKey="Kuczynski, J" uniqKey="Kuczynski J">J Kuczynski</name></author><author><name sortKey="Charlson, Es" uniqKey="Charlson E">ES Charlson</name></author><author><name sortKey="Zaneveld, J" uniqKey="Zaneveld J">J Zaneveld</name></author><author><name sortKey="Mozer, Mc" uniqKey="Mozer M">MC Mozer</name></author><author><name sortKey="Collman, Rg" uniqKey="Collman R">RG Collman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Appelt, S" uniqKey="Appelt S">S Appelt</name></author><author><name sortKey="Fancello, L" uniqKey="Fancello L">L Fancello</name></author><author><name sortKey="Le Bailly, M" uniqKey="Le Bailly M">M Le Bailly</name></author><author><name sortKey="Raoult, D" uniqKey="Raoult D">D Raoult</name></author><author><name sortKey="Drancourt, M" uniqKey="Drancourt M">M Drancourt</name></author><author><name sortKey="Desnues, C" uniqKey="Desnues C">C Desnues</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Groth, Ac" uniqKey="Groth A">AC Groth</name></author><author><name sortKey="Calos, Mp" uniqKey="Calos M">MP Calos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paabo, S" uniqKey="Paabo S">S Paabo</name></author><author><name sortKey="Poinar, H" uniqKey="Poinar H">H Poinar</name></author><author><name sortKey="Serre, D" uniqKey="Serre D">D Serre</name></author><author><name sortKey="Jaenicke Despres, V" uniqKey="Jaenicke Despres V">V Jaenicke-Despres</name></author><author><name sortKey="Hebler, J" uniqKey="Hebler J">J Hebler</name></author><author><name sortKey="Rohland, N" uniqKey="Rohland N">N Rohland</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Willerslev, E" uniqKey="Willerslev E">E Willerslev</name></author><author><name sortKey="Cooper, A" uniqKey="Cooper A">A Cooper</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Hyde, Er" uniqKey="Hyde E">ER Hyde</name></author><author><name sortKey="Haarmann, Dp" uniqKey="Haarmann D">DP Haarmann</name></author><author><name sortKey="Lynne, Am" uniqKey="Lynne A">AM Lynne</name></author><author><name sortKey="Bucheli, Sr" uniqKey="Bucheli S">SR Bucheli</name></author><author><name sortKey="Petrosino, Jf" uniqKey="Petrosino J">JF Petrosino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guinane, Cm" uniqKey="Guinane C">CM Guinane</name></author><author><name sortKey="Cotter, Pd" uniqKey="Cotter P">PD Cotter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bosshard, Pp" uniqKey="Bosshard P">PP Bosshard</name></author><author><name sortKey="Zbinden, R" uniqKey="Zbinden R">R Zbinden</name></author><author><name sortKey="Altwegg, M" uniqKey="Altwegg M">M Altwegg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cuiv, Po" uniqKey="Cuiv P">PO Cuiv</name></author><author><name sortKey="Klaassens, Es" uniqKey="Klaassens E">ES Klaassens</name></author><author><name sortKey="Durkin, As" uniqKey="Durkin A">AS Durkin</name></author><author><name sortKey="Harkins, Dm" uniqKey="Harkins D">DM Harkins</name></author><author><name sortKey="Foster, L" uniqKey="Foster L">L Foster</name></author><author><name sortKey="Mccorrison, J" uniqKey="Mccorrison J">J McCorrison</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Breton, J" uniqKey="Breton J">J Breton</name></author><author><name sortKey="Massart, S" uniqKey="Massart S">S Massart</name></author><author><name sortKey="Vandamme, P" uniqKey="Vandamme P">P Vandamme</name></author><author><name sortKey="De Brandt, E" uniqKey="De Brandt E">E De Brandt</name></author><author><name sortKey="Pot, B" uniqKey="Pot B">B Pot</name></author><author><name sortKey="Foligne, B" uniqKey="Foligne B">B Foligne</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ghanem, Fm" uniqKey="Ghanem F">FM Ghanem</name></author><author><name sortKey="Ridpath, Ac" uniqKey="Ridpath A">AC Ridpath</name></author><author><name sortKey="Moore, We" uniqKey="Moore W">WE Moore</name></author><author><name sortKey="Moore, Lv" uniqKey="Moore L">LV Moore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Appelt, S" uniqKey="Appelt S">S Appelt</name></author><author><name sortKey="Armougom, F" uniqKey="Armougom F">F Armougom</name></author><author><name sortKey="Le Bailly, M" uniqKey="Le Bailly M">M Le Bailly</name></author><author><name sortKey="Robert, C" uniqKey="Robert C">C Robert</name></author><author><name sortKey="Drancourt, M" uniqKey="Drancourt M">M Drancourt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Greenblatt, Cl" uniqKey="Greenblatt C">CL Greenblatt</name></author><author><name sortKey="Baum, J" uniqKey="Baum J">J Baum</name></author><author><name sortKey="Klein, By" uniqKey="Klein B">BY Klein</name></author><author><name sortKey="Nachshon, S" uniqKey="Nachshon S">S Nachshon</name></author><author><name sortKey="Koltunov, V" uniqKey="Koltunov V">V Koltunov</name></author><author><name sortKey="Cano, Rj" uniqKey="Cano R">RJ Cano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fornaciari, G" uniqKey="Fornaciari G">G Fornaciari</name></author><author><name sortKey="Zavaglia, K" uniqKey="Zavaglia K">K Zavaglia</name></author><author><name sortKey="Giusti, L" uniqKey="Giusti L">L Giusti</name></author><author><name sortKey="Vultaggio, C" uniqKey="Vultaggio C">C Vultaggio</name></author><author><name sortKey="Ciranni, R" uniqKey="Ciranni R">R Ciranni</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Santiago Rodriguez, Tm" uniqKey="Santiago Rodriguez T">TM Santiago-Rodriguez</name></author><author><name sortKey="Ly, M" uniqKey="Ly M">M Ly</name></author><author><name sortKey="Bonilla, N" uniqKey="Bonilla N">N Bonilla</name></author><author><name sortKey="Pride, Dt" uniqKey="Pride D">DT Pride</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ekeowa Anderson, Al" uniqKey="Ekeowa Anderson A">AL Ekeowa-Anderson</name></author><author><name sortKey="Harwood, Ca" uniqKey="Harwood C">CA Harwood</name></author><author><name sortKey="Perrett, Cm" uniqKey="Perrett C">CM Perrett</name></author><author><name sortKey="Sahota, A" uniqKey="Sahota A">A Sahota</name></author><author><name sortKey="Annan, H" uniqKey="Annan H">H Annan</name></author><author><name sortKey="Ran, H" uniqKey="Ran H">H Ran</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Favre, M" uniqKey="Favre M">M Favre</name></author><author><name sortKey="Obalek, S" uniqKey="Obalek S">S Obalek</name></author><author><name sortKey="Jablonska, S" uniqKey="Jablonska S">S Jablonska</name></author><author><name sortKey="Orth, G" uniqKey="Orth G">G Orth</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ong, Ck" uniqKey="Ong C">CK Ong</name></author><author><name sortKey="Chan, Sy" uniqKey="Chan S">SY Chan</name></author><author><name sortKey="Campo, Ms" uniqKey="Campo M">MS Campo</name></author><author><name sortKey="Fujinaga, K" uniqKey="Fujinaga K">K Fujinaga</name></author><author><name sortKey="Mavromara Nazos, P" uniqKey="Mavromara Nazos P">P Mavromara-Nazos</name></author><author><name sortKey="Labropoulou, V" uniqKey="Labropoulou V">V Labropoulou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wright, Gd" uniqKey="Wright G">GD Wright</name></author><author><name sortKey="Poinar, H" uniqKey="Poinar H">H Poinar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Clemente, Jc" uniqKey="Clemente J">JC Clemente</name></author><author><name sortKey="Pehrsson, Ec" uniqKey="Pehrsson E">EC Pehrsson</name></author><author><name sortKey="Blaser, Mj" uniqKey="Blaser M">MJ Blaser</name></author><author><name sortKey="Sandhu, K" uniqKey="Sandhu K">K Sandhu</name></author><author><name sortKey="Gao, Z" uniqKey="Gao Z">Z Gao</name></author><author><name sortKey="Wang, B" uniqKey="Wang B">B Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Levine, Dp" uniqKey="Levine D">DP Levine</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suarez, Av" uniqKey="Suarez A">AV Suarez</name></author><author><name sortKey="Tsutsui, Nd" uniqKey="Tsutsui N">ND Tsutsui</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Italie</li><li>États-Unis</li></country><region><li>Californie</li><li>Texas</li><li>Toscane</li></region><settlement><li>Pise</li></settlement><orgName><li>Université de Pise</li></orgName></list><tree><noCountry><name sortKey="Toranzos, Gary A" sort="Toranzos, Gary A" uniqKey="Toranzos G" first="Gary A." last="Toranzos">Gary A. Toranzos</name></noCountry><country name="États-Unis"><region name="Californie"><name sortKey="Santiago Rodriguez, Tasha M" sort="Santiago Rodriguez, Tasha M" uniqKey="Santiago Rodriguez T" first="Tasha M." last="Santiago-Rodriguez">Tasha M. Santiago-Rodriguez</name></region><name sortKey="Cano, Raul J" sort="Cano, Raul J" uniqKey="Cano R" first="Raul J." last="Cano">Raul J. Cano</name><name sortKey="Dowd, Scot E" sort="Dowd, Scot E" uniqKey="Dowd S" first="Scot E." last="Dowd">Scot E. Dowd</name></country><country name="Italie"><region name="Toscane"><name sortKey="Fornaciari, Gino" sort="Fornaciari, Gino" uniqKey="Fornaciari G" first="Gino" last="Fornaciari">Gino Fornaciari</name></region><name sortKey="Fornaciari, Gino" sort="Fornaciari, Gino" uniqKey="Fornaciari G" first="Gino" last="Fornaciari">Gino Fornaciari</name><name sortKey="Luciani, Stefania" sort="Luciani, Stefania" uniqKey="Luciani S" first="Stefania" last="Luciani">Stefania Luciani</name><name sortKey="Marota, Isolina" sort="Marota, Isolina" uniqKey="Marota I" first="Isolina" last="Marota">Isolina Marota</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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